Edaravone, sold as under the brand names Radicava and
Radicut, is an intravenous medication used to help with recovery following a
stroke and to treat amyotrophic lateral sclerosis (ALS). The label carries a
warning about the potential for hypersensitivity reactions to edaravone, and
adverse effects include bruising, gait disturbances, headache, skin
inflammation, eczema, problems breathing, excess sugar in urine, and fungal
skin infections. The mechanism by which edaravone might be effective is
unknown. The drug is known to be an antioxidant, and oxidative stress has been
hypothesized to be part of the process that kills neurons in people with ALS.
Amyotrophic lateral sclerosis (ALS)
Amyotrophic
lateral sclerosis (ALS), also known as motor neurone disease (MND) or Lou
Gehrig's disease, is a disease that causes the death of neurons controlling
voluntary muscles. Some also use the term motor neuron disease for a group of
conditions of which ALS is the most common. ALS is characterized by stiff
muscles, muscle twitching, and gradually worsening weakness due to muscles
decreasing in size. It may begin with weakness in the arms or legs, or with
difficulty speaking or swallowing. About half of the people affected develop at
least mild difficulties with thinking and behavior and most people experience
pain. Most eventually lose the ability to walk, use their hands, speak,
swallow, and breathe.
Uses
Edaravone
is used to treat a certain type of nerve disease called amyotrophic lateral
sclerosis (ALS, also commonly called Lou Gehrig's disease). It helps to slow
down the worsening of this disease. However, it is not a cure for ALS, and it
does not reverse nerve damage or muscle weakness.
How to use Edaravone
Read
the Patient Information Leaflet if available from your pharmacist before you
start using edaravone and with each treatment cycle. If you have any questions,
ask your doctor or pharmacist.
Side Effects
Bruising,
problems walking, or headache may occur. If any of these effects last or get
worse, tell your doctor or pharmacist promptly.
Precautions
Before
using edaravone, tell your doctor or pharmacist if you are allergic to it; or
if you have any other allergies. This product may contain inactive ingredients
(including sulfites such as sodium bisulfite), which can cause allergic
reactions or other problems. Talk to your pharmacist for more details.
Interactions
Drug
interactions may change how your medications work or increase your risk for
serious side effects. This document does not contain all possible drug
interactions. Keep a list of all the products you use (including prescription/non-prescription
drugs and herbal products) and share it with your doctor and pharmacist. Do not
start, stop, or change the dosage of any medicines without your doctor's
approval.
Overdose
If
someone has overdosed and has serious symptoms such as passing out or trouble
breathing, call 911. Otherwise, call a poison control center right away. US
residents can call their local poison control center at 1-800-222-1222. Canada
residents can call a provincial poison control center.
Storage
Store
at room temperature. Protect from light. Store in the overwrap package until
you are ready to use. Once the overwrap package is opened, use the medication
within 24 hours. See the product information for more details. Keep all
medications away from children and pets.
Related Links
https://en.wikipedia.org/wiki/Edaravone
https://en.wikipedia.org/wiki/Amyotrophic_lateral_sclerosis
https://www.webmd.com/drugs/2/drug-173632/edaravone-intravenous/details
#Edaravone
Injection #Amyotrophic lateral sclerosis #Radicut 30mg 10s (JP) #Mitsubishi #Aravon
30mg 1s #Sun #
Please note: The Content is not intended to be a substitute for
professional medical advice, diagnosis, or treatment. Always seek the advice of
your physician or other qualified health providers with any questions you may
have regarding a medical condition.